Filmet Oral Suspension

✔️ Uses of Filmet Oral Suspension

• Treatment of Bacterial Infections
• Treatment of Parasitic Infections

✔️ How to use Filmet Oral Suspension

Suspension: 

• Shake the bottle well before use.
• Check the label for directions and take it with or without food in doses as prescribed by the doctor with the help of a measuring cup.

✔️ How Filmet Oral Suspension works

Filmet is an antibiotic. It kills the bacteria and other microorganisms that cause infections by damaging their DNA.

✔️ What if you forget to take Filmet?

If you miss a dose of Filmet, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose

✔️ Side effects of Filmet Oral Suspension

• Headache
• Dryness in mouth
• Nausea
• Metallic taste

✔️ Quick Suggestions:

• Filmet treats infections caused by bacteria and parasites.
• It may cause side effects like nausea, stomach upset, and a metallic taste in the mouth.
• Filmet used in a high dose or for a prolonged time increases the risk of side effects such as nerve damage. Take it only as prescribed by your doctor.
• Do not drink or eat a lot of caffeine-containing products such as coffee, tea, energy drinks, cola, or chocolate. Filmet 60ml may increase nervousness, sleeplessness, and anxiety caused by caffeine.
• Inform your doctor if you have liver disease. Your dose may need to be adjusted in severe liver disease.

✔️ Indications of Filmet Oral Suspension

Filmet Oral Suspension is a versatile antibiotic medicine that can be used to treat many different infections caused by bacteria. These include infections of the blood, brain, lungs, bones, joints, urinary tract, stomach, and intestines. It can also be used to treat gum ulcers and other dental infections (abscesses), leg ulcers, and pressure sores. It works by stopping the growth of the bacteria causing the infection.

✔️ Pharmacology

Metronidazole is an antibacterial medication that belongs to the imidazole class and is used as an antiprotozoal agent. Anaerobes decrease the 5-nitro group of Metronidazole metabolically. Metronidazole's bactericidal activity is due to the reduced form of the antibiotic interacting with DNA, according to studies.

✔️ Dosage & Administration of Filmet Oral Suspension

Tablet and Suspension:

Trichomoniasis (Adults & Children over 10 yrs)-

• 200 mg tid or 400 mg bid for 7 days
• 800 mg in the morning and 1-2 gm at night for 2 days
• 2 gm as a single dose for 1 day

Trichomoniasis (Children)-

• Children 7-10 yrs: 100 mg tid
• Children 3-7 yrs: 100 mg bid
• Children 1-3 yrs: 50 mg tid

Intestinal amoebiasis (Adults & Children over 10 yrs)- 

• 800 mg tid for 5 days

Intestinal amoebiasis (Children)-

• Children 7-10 yrs: 400 mg tid
• Children 3-7 yrs: 200 mg qid
• Children 1-3 yrs: 200 mg tid

Extra-intestinal & Asymptomatic amoebiasis (Adults & Children over 10 yrs)-

• 400-800 mg tid for 5-10 days

Extra-intestinal & Asymptomatic amoebiasis (Children)-

• Children 7-10 yrs: 200-400 mg tid
• Children 3-7 yrs: 100-200 mg qid
• Children 1-3 yrs: 100-200 mg tid

Giardiasis (Adults & Children over 10 yrs)-

• 2 gm once daily for 3 days

Giardiasis (Children)-

• Children 7-10 yrs: 1 gm once daily
• Children 3-7 yrs: 600-800 mg once daily
• Children 1-3 yrs: 500 mg once daily

Acute ulcerative gingivitis (Adults & Children over 10 yrs)-

• 200 mg tid for 3 days

Acute ulcerative  gingivitis (Children)-

• Children 7-10 yrs: 100 mg tid
• Children 3-7 yrs: 100 mg bid
• Children 1-3 yrs: 50 mg tid

Acute dental infections (Adults & Children over 10 yrs)-

• 200 mg tid for 3-7 days

Anaerobic infections (Adults & Children over 10 yrs)-

• 800 mg initially and then 400 mg tid for 7 days

Anaerobic infections (Children)-

• Children 1-10 yrs: 7.5 mg/kg tid

Surgical prophylaxis (Adults & Children over 10 yrs)-

• 400 mg tid started 24  hours before  surgery for 1 day

Surgical prophylaxis (Children)-

• Children 1-10 yrs: 7.5 mg/kg tid

Bacterial Vaginosis (Adults & Children over 10 yrs)-

• 400 mg bid for 7 days
• 2 gm as a single dose for 1 day

Leg ulcers and pressure sores (Adults & Children over 10 yrs)-

• 400 mg tid for 7 days

✔️ Interaction

Disulfiram: Patients using metronidazole and disulfiram at the same time have experienced psychotic responses.

Because of the risk of a disulfiram-like (antabuse effect) reaction, alcoholic beverages and medications containing alcohol should be avoided during therapy and for at least one day following (flushing, vomiting, tachycardia). Warfarin-type oral anticoagulant therapy: Reduced hepatic catabolism causes potentiation of the anticoagulant action and increased hemorrhagic risk. During metronidazole medication, prothrombin time should be evaluated more regularly and anticoagulant therapy altered if co-administration is used. Metronidazole can raise lithium levels in the bloodstream.

• When co-administration of cyclosporin and creatinine is required, serum cyclosporin and serum creatinine should be regularly monitored.
• Metronidazole elimination is accelerated with phenytoin or phenobarbital, resulting in lower plasma levels.
• 5-Fluorouracil: A decrease in 5-fluorouracil clearance leads to an increase in 5-fluorouracil toxicity.
• Busulfan: Metronidazole can raise busulfan levels in the blood, resulting in severe busulfan toxicity.

✔️ Contraindications

Patients having a history of hypersensitivity to Metronidazole or other Nitroimidazole derivatives should avoid taking it.

✔️ Pregnancy & Lactation

• Metronidazole is classified as a pregnancy category B by the US Food and Drug Administration. However, no suitable and well-controlled studies on pregnant women have been conducted. Because animal reproduction studies do not always predict human response, this medication should only be used during pregnancy if absolutely necessary.
• Human milk has been found to contain metronidazole. When Metronidazole is given to a breastfeeding mother, caution should be observed.

✔️ Precautions & Warnings

• If Metronidazole must be given for a longer period of time than is generally indicated, it is recommended that hematological tests, particularly leucocyte counts, be performed on a regular basis and that patients be watched for adverse responses such as peripheral or central neuropathy (such as paresthesia, ataxia, dizziness, convulsive seizures).
• Patients with hepatic encephalopathy should be given metronidazole with caution.
• Metronidazole might cause urine to discolor, thus patients should be cautioned.
• You should consult a doctor if you have symptoms associated with dehydration like dry mouth, excessive thirst, wrinkled skin, little or no urination, dizziness and lightheadedness.

✔️ Storage Conditions

Store below 30°C. Keep protected from light. Keep medicines out of the reach of children. Do not use it later than the date of expiry.